You enjoy running. You also enjoy pushing yourself harder to extend your limits. But while doing so, if you suffer from severe muscle pain and weakness, nausea, and fatigue, don’t ignore! Chances are that you have Rhabdomyolysis and need immediate medical attention.
Rhabdomyolysis is condition where the cell components are released into the bloodstream due to severe muscle cells and tissue damage. In this situation, the protein myoglobin and the enzyme Creatine Phosphokinase (CPK) is of particular importance among other cell components. Myoglobin is the primary oxygen storage protein in muscle tissues and is quite similar to hemoglobin found in the blood. Normally, Myoglobin is not found in the blood and its presence affects the functioning of the kidney. Myoglobin crystallizes and blocks the kidney tubules. This causes the dark colored urine and can lead to kidney damage and renal failure in extreme situations.
While the CPK enzyme itself if not harmful, it serves as an indicator for myoglobin. A rapid increase in the CPK level indicates Rhabdomyolysis. In human the normal CPK levels are around 200 U/L. Rhabdomyolysis is diagnosed when the CPK level rises above 10,000 U/L.What are the causes?
Damage to muscle tissues and cells can occur due to extreme conditions. These conditions can be due to both traumatic and non-traumatic conditions.
Traumatic conditions -
You can prevent Rhabdomyolysis by ensuring the following steps -
It is important that you learn to listen to your body. Don’t push yourself too hard and watch out for the warning signs. If you are tired then take some time off and if you show some signs and symptoms discussed here, see a doctor immediately.